Evaluation of doppler indices of maternal uterine artery in cases with early idiopathic recurrent abortion

This study was performed on 120 pregnant women at early pregnancy. They were divided into two groups: The control group [I] included 30 normal pregnant women with no history of abortion and the study group [II] included 90 pregnant women with history of two or more unexplained abortion who were further subdivided randomly into three subgroups. All patients in the subgroups were given folic acid and low-dose aspirin; they were given alone to patients in group IIa, patients in group IIb received also nitroglycerine 5 TTS skin patches [5 mg each] and patients in group IIc were given 1.2 MIU of long- acting penicillin every two weeks. Doppler study of the uterine artery blood flow was performed at the time of vaginal ultrasound examination at different intervals of gestational age for all patients in all groups. A follow up of pregnancy was done every 2 weeks till 20 weeks [age of viability] or abortion occurred. The study concluded that uterine artery Doppler indices [resistivity index, RI, and pulsatility index, PI] significantly decreased with the increasing gestational age. Treatment with folic acid, pediatric aspirin, nitroglycerine patches and long-acting penicillin resulted in Doppler indices close to the control group results and in a better pregnancy outcome

Cyanobacteria of hammam faroun hot spring [Sinai-Egypt]

In this study, twenty-eight cyanobacterial taxa were identified. On the basis of temperature tolerance, it was found that the species had different thermal ranges of growth; some had a wide thermal range of growth [30 - 72C], while others were characterized by a narrow range [30 - 40C]. Some species grew only at temperature [30 or 72C] such as Merismopedia punctata and Phormidium tenue, respectively. The biocecological analysis indicated that the spring had a clean oligosaprobic character with tendency to the presence of alpha- mezosaprbic indicators such as Oscillatoria tenuis

Progesterone receptors content of the endometrium in patients with luteal phase defect and its relationship to endometrium maturation and serum progesterone level

Luteal phase defect [LPD], a disorder characterized by delayed secretory endometrial maturation is associated with infertility and/or recurrent abortion. This endometrial retardation may not be a result of deficient progesterone secretion, but rather a consequence of endometrial failure to respond adequately to progesterone stimulation. This study included 20 patients with LPD suffering of infertility or habitual abortion and 20 control cases. All cases were subjected to endometrial biopsy on the 26th day of the cycle to assess maturation, immunostaining of the endometrial tissue for progesterone receptor content and serum progesterone level on the 25th and 26th days of the same cycle. The endometrial maturation had a lag of 4.46 days in infertile cases and 4.86 days in habitual aborters. The difference was insignificant. The serum progesterone levels showed no significant difference between study and control cases. The glandular progesterone receptors were higher in LPD cases, while stromal receptors were more in the control cases. These results suggested that serum progesterone determination is not ideal for LPD prediction. Estimation of progesterone receptors in the endometrium is valuable as failure of down regulation of glandular progesterone receptors in late luteal phase may be an etiologic factor in LPD